| Product Name | Anti-Cytokeratin pan Monoclonal Antibody |
|---|---|
| Description | Cytokeratins are precisely regulated in tissue and little is known about the molecular mechanisms underlying this regulation. However, the expression pattern of cytokeratin 6 is known to be particularly complex. It is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Mouse monoclonal Antibody to Cytokeratin pan. Lu-5 represents an excellent marker for all types of epithelia. Ideal marker for immunolocalization studies on frozen and paraffin embedded tissue. |
| Clonality | Monoclonal |
| Clone | Lu5 |
| Immunogen | Cells of lung cancer cell line A549 and A2182 |
| Isotype | Mouse IgG1 |
| Specificity | Useful for distinguishing carcinomas from non- epithelial tumors. Tumors specifically detected: all epithelium-derived neoplasms. The antibody is suitable for discriminating of keratinizing and non-keratinizing squamous cell carcinoma versus e.g. poorly differentiated adenocarcinoma. |
| Reactivity | Amphibian, Gallus, Bovine, Human, Rat, Snake |
| Form | Purified, 0.09 % sodium azide, 0.5% BSA in PBS buffer, pH 7.4 |
| Storage | 2-8C for immediate use, or at -2°C (aliquot) |
| Background | Cytokeratins are precisely regulated in tissue and little is known about the molecular mechanisms underlying this regulation. However, the expression pattern of cytokeratin 6 is known to be particularly complex. It is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. |
| Supplier | ARP |
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