| Product Name | Anti-Cytokeratin 8/18, Monoclonal Antibody |
|---|---|
| Description | Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This monoclonal antibody recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained._ |
| Synonyms | CARD2, CK8, CYK8, CYKER, Cytokeratin Endo A, DreK8, EndoA, K2C8, K8, Keratin 8, Krt 2.8, KRT8, Type-II Keratin Kb8. Cell Proliferation-inducing Gene 46 Protein, CK18, CYK18 Cytokeratin Endo B, K18, Keratin-18, Kerd, KRT18 |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | C-51 |
| Immunogen | Cytoskeleton preparation from HeLa cells |
| Isotype | IgG1, kappa |
| Reactivity | Amphibian, Gallus, Bovine, Donkey, Ferret, Human, Porcine, Primate, Rabbit, Rat, Sheep |
| Applications | FC, IF, IHC, WB |
| Form | 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Gene Id | 3856 (CK8); 3875 (CK18) |
| Uniprot | P05787 (CK8); P05783 (CK18) |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | Bartek et al. J. Pathology,164:215-24 (1991).Bartkova et al. Neoplasma 38(4), 439-46 (1991). |
| Supplier | ARP |
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