| Product Name | Anti-EMR2 Antibody [2A1] (PE) |
|---|---|
| Description | Mouse monoclonal [2A1] antibody to EMR2 (PE). |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 2A1 |
| Conjugate | PE |
| Immunogen | NIH/3T3 cells stably transfected with EMR2 (EGF1-5) cDNA. |
| Isotype | IgG1 |
| Target | EMR2 |
| Specificity | This antibody recognises human EMR2, a member of the epidermal growth factor-seven transmembrane (EGF-TM7) family of proteins, which is closely related to CD97. EMR2, also known as CD312, is predominantly expressed on myeloid dendritic cells, monocytes and tissue macrophages. Various isoforms of EMR2 have been documented. The ligand for the largest isoform of EMR2 has recently been identified as chrondroitin sulphate, which binds to the fourth EGF-like module of EMR2. recognises the stalk region of EMR2. |
| Reactivity | Human |
| Applications | FC |
| Working Dilutions | Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 106 cells in 100µl. |
| Form | Lyophilized |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide. |
| Concentration | Reconstitution dependent. |
| Storage | Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Supplier | Antibodies.com |
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