| Product Name | Anti-ErbB2 / HER2 Antibody [ERBB2/7158R] - BSA and Azide free |
|---|---|
| Description | Recombinant rabbit monoclonal [ERBB2/7158R] antibody to ErbB2 / HER2. |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | ERBB2/7158R |
| Conjugate | Unconjugated |
| Immunogen | Recombinant fragment (around Amino Acids 1055-1255) of human ERBB2 encoding cytoplasmic domain. The exact sequence is proprietary. |
| Isotype | IgG |
| Molecular Weight | 185 kDa |
| Target | ErbB2 / HER2 |
| Specificity | Recognizes a protein of 185kDa, which is identified as c-erbB-2/HER-2/neu. Its epitope is localized in the extracellular domain. C-erbB-2/HER-2 is a member of the EGFR family. This MAb is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary. |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free. |
| Concentration | 1 mg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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