Anti-Estrogen Receptor, alpha (Marker of Estrogen Dependence), Monoclonal Antibody

Category: Antibodies
Catalog
24-2099-MSM5
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Product Name Anti-Estrogen Receptor, alpha (Marker of Estrogen Dependence), Monoclonal Antibody
Description This monoclonal antibody is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this monoclonal antibody is mapped between aa120-170. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
Synonyms Estrogen Receptor alpha delta 4*5,6,7*/654 isoform, Estrogen Receptor alpha delta 4 +49 isoform, Nuclear receptor subfamily 3 group A member 1
Host Mouse
Clone AER314
Immunogen ER purified from cow uterus
Isotype IgG1
Reactivity Bovine, Human, Mouse, Rabbit, Rat
Applications FC, IF
Form 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Gene Id 2099
Uniprot P03372
Storage Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
References Abbondanza C et. al. Steroids, 1993, 58:4-12
Supplier ARP

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