| Product Name | Anti-Fas Antibody [C02-6C8] (Biotin) |
|---|---|
| Description | Mouse monoclonal [C02-6C8] antibody to Fas (Biotin). |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | C02-6C8 |
| Conjugate | Biotin |
| Immunogen | E. coli derived recombinant human full length CD95 (Gln26-Val335). |
| Isotype | IgG1 |
| Target | Fas |
| Specificity | This antibody recognises CD95, also known as TNFRSF6, Apo-1 antigen, apoptosis-mediating surface antigen FAS and FASLG receptor. It is a member of the TNF receptor superfamily and is a death receptor. CD95 is a type I transmembrane glycoprotein which is ubiquitously expressed, but it is particularly abundant in the thymus, liver, heart and kidney tissues. Upon binding of its ligand CD95L, CD95 interacts with adaptor proteins to form a death-inducing signaling complex to trigger a cell death signal. However CD95 is also able to promote inflammation, normal and tumor cell growth and migration through other signaling pathways including PI3K, NF?B and JNK MAPKs. The biotinylated Mouse anti Human CD95 antibody, clone C02-6C8 (MCA6273B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human CD95 antibody, clone E06-1A9 (MCA6272GA) as the capture antibody. |
| Reactivity | Human |
| Applications | ELISA |
| Working Dilutions | ELISA: 1 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide. |
| Concentration | 100 µg/ml |
| Storage | Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light. |
| Supplier | Antibodies.com |
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