| Product Name | Anti-Fas Ligand Antibody [10F2] - BSA and Azide free |
|---|---|
| Description | Mouse monoclonal [10F2] antibody to Fas Ligand. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 10F2 |
| Conjugate | Unconjugated |
| Isotype | IgG1 |
| Target | Fas Ligand |
| Specificity | This antibody recognises the human CD178 cell surface antigen, a ~40 kDa glycoprotein also known as Fas ligand (CD95L).CD178 is a member of the TNF family, which is expressed by activated T lymphocytes and NK cells. The protein may exist as either a membrane bound or a cleaved soluble form. CD178 plays an important role in T cell development and cytotoxicity. Binding of CD178 to Fas (CD95) results in the induction of apoptosis. Mouse anti Human CD178 antibody, clone 10F2 is reported to block the activity of Fas ligand. |
| Reactivity | Human |
| Applications | ELISA, FA, FC, IP |
| Working Dilutions | Flow Cytometry: 1:25 - 1:50, Use 10µl of the suggested working dilution to label 1x106 cells in 100µl |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline. |
| Concentration | 1 mg/ml |
| Storage | Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Supplier | Antibodies.com |
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