| Product Name | Anti-FBP2 (clone AT1E11) |
|---|---|
| Description | FBP2 (Fructose-1,6-bisphosphatase isozyme 2) is a 339 amino acid protein. FBP2 belongs to the FBPase class 1 family. The hydrolysis of fructose-1,6-bisphosphate to fructose-6-phosphate is a key reaction of carbohydrate metabolism. The enzyme that catalyzes this reaction appears to be present in all forms of living organisms. FBPase is encoded by two genes, FBP1 and FBP2, which express the liver and muscle isoforms, respectively. FBPase is regulated by AMP inhibition in most species. Inhibition of FBPase by AMP affects the turnover of bound substrate and not its affinity for substrate. |
| Synonyms | Fructose-1,6-bisphosphatase isozyme 2, |
| Host | Mouse |
| Clone | AT1E11. Anti-human FBP2 mAb, clone AT1E11, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human FBP2 protein. |
| Immunogen | Recombinant human FBP2 (1-339aa) purified from E. coli |
| Isotype | IgG1,K |
| Reactivity | Human, Mouse |
| Applications | ELISA, WB, Dot Blot |
| Form | Purified, in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide |
| Storage | Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles. |
| References | Dzugaj, A., et al. (1980) Biochim Biophys Acta 614: 407-412Marcus, F., et al. (1987) Arch Biol Med Exp 20: 371-378Matsuura, T., et al. (2002) Mol Genet Metab 76: 207-210 |
| Supplier | ARP |
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