| Product Name | Anti-Fibrinogen Antibody [40F11] |
|---|---|
| Description | Mouse monoclonal [40F11] antibody to Fibrinogen. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 40F11 |
| Conjugate | Unconjugated |
| Immunogen | Fibrin degradation products. |
| Isotype | IgG1 |
| Target | Fibrinogen |
| Specificity | This antibody recognises human fibrinogen, a glycoprotein produced in the liver. Fibrinogen is a hexamer, consisting of two sets of three subunits (alpha, beta and gamma). Thrombin converts fibrinogen into fibrin, which is then cross-linked by factor XIII to form a blood clot. recognises fibrin degradation products (FDPs), substances that are left behind after a blood clot dissolves. This process, called fibrinolysis, is produced by the action of enzymes such as plasmin on fibrin. One FDP is D-dimer, levels of which can be used to diagnose deep vein thrombosis or pulmonary embolism. The fibrinolytic system is also closely linked to the control of inflammation. |
| Reactivity | Human |
| Applications | ELISA, WB |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide. |
| Concentration | 1 mg/ml |
| Storage | Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. |
| Supplier | Antibodies.com |
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