| Product Name | Anti-Fibrinogen Antibody (FITC) |
|---|---|
| Description | Sheep polyclonal antibody to Fibrinogen (FITC). |
| Host | Sheep |
| Clonality | Polyclonal |
| Conjugate | FITC |
| Immunogen | Human fibrinogen purified from plasma. |
| Isotype | IgG |
| Target | Fibrinogen |
| Specificity | This antibody recognises human fibrinogen, a complex ~340 kDa hetero-hexameric (di-trimeric) glycoprotein consisting of 3 pairs of α, β and γ chains linked by a series of 29 disulphide bonds. The six chains are arranged in such a way that all the N-Terminal ends adjoin to form a central E domain with two trimeric coiled coil structures connecting to outer D domains. Fibrinogen plays an important role in the coagulation process with the D and E domains interacting via the C-terminal ends of the α chains during fibrin clot cross-linking. Sheep anti human fibrinogen antibody shows minimal cross-reactivity with related serum proteins. Fibrinogen has been identified as a ferritin binding protein in the horse. Sheep anti human fibrinogen antibody has been successfully as a capture reagent for ferritin - anti ferritin IgG complexes in horse plasma to evaluate the antibody response to ferritin by ELISA. |
| Reactivity | Human, Mouse, Rat |
| Applications | IF |
| Working Dilutions | IF: 1:10 - 1:100 |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide. |
| Concentration | 1 mg/ml |
| Storage | Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light. |
| Supplier | Antibodies.com |
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