| Product Name | Anti-Fibronectin Monoclonal Antibody |
|---|---|
| Description | This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined. Fibronectin seems to play a key role in the tumor cell extracellular adhesion matrix during invasive growth. Increasing expression of stromal fibronectin has been reported during tumor progression. |
| Synonyms | FN, CIG, FNZ, MSF, ED-B, FINC, GFND, LETS, GFND2 |
| Clonality | Monoclonal |
| Clone | 568 |
| Immunogen | Fibronectin cultivated human fibroblasts |
| Isotype | IgG1 |
| Specificity | Mab 568 reacts with the cell binding part of the fibronectin molecule |
| Reactivity | Human |
| Applications | IHC, WB |
| Form | Hybridoma culture supernatant |
| Storage | 2-8C |
| References | Christensen, L. et al. (1992), APMIS, Suppl. 26: 1-39 |
| Background | This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined. |
| Supplier | ARP |
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