Anti-Fibronectin (8th Type III Repeat), Monoclonal Antibody
| Product Name | Anti-Fibronectin (8th Type III Repeat), Monoclonal Antibody |
|---|---|
| Description | Epitope of this monoclonal antibody is located in the 8th type III repeat in the cell-binding region of fibronectin. Fibronectins are disulfide-linked, dimeric glycoproteins of ~440kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectins are involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This monoclonal antibody is excellent for staining of formalin-fixed, paraffin-embedded tissues. |
| Synonyms | Cold insoluble globulin (CIG), FINC, FN1, FNZ, GFND, GFND2, LETS, Migration stimulating factor (MSF), Ugl-Y3 |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 568 |
| Immunogen | High molecular weight proteins secreted by cultivated human fibroblasts |
| Isotype | IgG1, kappa |
| Reactivity | Human |
| Applications | FC, IF, IHC |
| Form | 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Gene Id | 2335 |
| Uniprot | P02751 |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | Christensen, L., et al., APMIS, 98(7), 615-623 (1990).Christensen, L., et al., APMIS, suppl. 26, 1-39 (1992).Ljubimov AV et. al. Lab Investigation, 1995; 72:461-473 |
| Supplier | ARP |
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