| Product Name | Anti-FKBP14 (AT3F4) |
|---|---|
| Description | The FK506-binding proteins (FKBPs) are a unique group of chaperones found in a wide variety of organisms. The gene encoding FKBP14 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Many of these functions are mediated by specific domains that adopt distinct tertiary conformations. In humans, FKBP14 possess variable numbers of FKBP domains and are associated with the endoplasmic reticulum (ER). FK506 Binding Protein 14, 22 KDa (FKBP14) subcellular located cytoplasm, endoplasmic reticulum lumen. FKBP14 majer molecular functions are calcium ion binding, isomerase activity, peptidyl-prolyl cis-trans isomerase activity. |
| Synonyms | FKBP22, Peptidyl-prolyl cis-trans isomerase FKBP14, 22 kDa FK506 binding protein, FK506 binding protein 14 (22 kDa), FK506 binding protein 14, FKBP 22, FKBP22, Peptidyl prolyl cis trans isomerase, PPIase, Rotamase |
| Host | Mouse |
| Clone | AT3F4. Anti-human FKBP14 mAb, clone AT3F4, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human FKBP14 protein. |
| Immunogen | Recombinant human FKBP14 (20-211aa) purified from E. coli |
| Isotype | K,IgG2b |
| Reactivity | Human, Mouse |
| Applications | ELISA, WB, Dot Blot |
| Form | Purified, in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide |
| Storage | Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles. |
| References | Somarelli J. A, et al. (2008) Proteins, 72(1): 197-208. Flores I, et al. (2007) Fertil Steril, 87(5):1180-99. Tremmel, D, et al. (2007) FEBS Lett, 581(10):2036-40. |
| Supplier | ARP |
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