Anti-FKBP6 (clone AT9B7)

Antibodies, Monoclonal Antibodies
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Product Name Anti-FKBP6 (clone AT9B7)
Description FKBP6 (FK506 binding protein 6) is a 327 amino acid protein. FKBP6 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP6 is essential for homologous chromosome pairing in meiosis during spermatogenesis. FKBP6 is ubiquitously expressed in all tissues, with higher expressed in testis, heart, skeletal muscle, liver, and kidney. Deletion of FKBP6 may contribute to hypercalcemia and growth delay in Williams-Beuren syndrome.
Reactivity Human
Applications Dot blot, ELISA, WB
Clone Anti-human FKBP6 mAb, clone AT9B7, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human FKBP6 protein.
Concentration 0.1mg/ml
Form Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.02% Sodium Azide.
Species Mouse
Host Mouse
Isotype IgG1, K
Immunogen Recombinant human FKBP6 (1-327aa) purified from E. coli
NCBI Number NP_003593
References Meng. X., et al. (1998) Genomics 52: 130-137Crackower. M.A., et al. (2003) Science 300: 1291-1295Metcalfe. K., et al. (2005) Clin Dysmorphol 14: 61-65
Storage Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
Synonyms FKBP36, PPIase FKBP6, FK506 binding protein 6, 36kDa 36 kDa FK506 binding protein, EC, FK506 binding protein 6, FKBP 36, Immunophilin FKBP36, Peptidyl prolyl cis trans isomerase, PPIase, Rotamase.
Working Dilutions Optimal dilution should be performed by user.

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