| Product Name | Anti-FKBP6 (clone AT9B7) |
|---|---|
| Description | FKBP6 (FK506 binding protein 6) is a 327 amino acid protein. FKBP6 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP6 is essential for homologous chromosome pairing in meiosis during spermatogenesis. FKBP6 is ubiquitously expressed in all tissues, with higher expressed in testis, heart, skeletal muscle, liver, and kidney. Deletion of FKBP6 may contribute to hypercalcemia and growth delay in Williams-Beuren syndrome. |
| Synonyms | FKBP36, PPIase FKBP6, FK506 binding protein 6, 36kDa 36 kDa FK506 binding protein, EC 5.2.1.8, FK506 binding protein 6, FKBP 36, Immunophilin FKBP36, Peptidyl prolyl cis trans isomerase, PPIase, Rotamase. |
| Host | Mouse |
| Clone | Anti-human FKBP6 mAb, clone AT9B7, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human FKBP6 protein. |
| Immunogen | Recombinant human FKBP6 (1-327aa) purified from E. coli |
| Isotype | IgG1,K |
| Reactivity | Human, Mouse |
| Applications | ELISA, WB, Dot Blot |
| Form | Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.02% Sodium Azide. |
| Storage | Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles. |
| References | Meng. X., et al. (1998) Genomics 52: 130-137Crackower. M.A., et al. (2003) Science 300: 1291-1295Metcalfe. K., et al. (2005) Clin Dysmorphol 14: 61-65 |
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