| Product Name | Anti-FRA2 Antibody [PCRP-FOSL2-1B1] |
|---|---|
| Description | Mouse monoclonal [PCRP-FOSL2-1B1] antibody to FRA2. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | PCRP-FOSL2-1B1 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant full-length human FOSL2 protein. |
| Isotype | IgG1 |
| Molecular Weight | 40 kDa |
| Target | FRA2 |
| Specificity | The Fos related gene, Fra-2, was initially molecularly cloned from chicken genomic DNA and shown to represent a new member of the immediate early gene family. The human counterpart of the chicken Fra-2 gene has since been described. Sequence alignment shows that the amino acid sequences conserved among Fra-2, c-Fos, Fra-1 and Fos B are contained in five regions. Region 2, the longest and most highly conserved region, contains the leucine zipper structure and the basic region, suggesting that like Fos, Fra-1 and Fos B, Fra-2 also forms heterodimers with c-Jun that recognize a specific DNA sequence such as the binding site for transcription factor AP-1. Such a model is further supported by the finding that the Fra-2 gene product forms a complex with c-Jun in growth-stimulated cells |
| Reactivity | Human |
| Applications | FC, IF |
| Working Dilutions | Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide. |
| Concentration | 200 µg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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