Anti-FSH-beta (Follicle Stimulating Hormone-beta), Monoclonal Antibody
Product Name | Anti-FSH-beta (Follicle Stimulating Hormone-beta), Monoclonal Antibody |
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Description | This monoclonal antibody reacts with a protein of 22kDa, identified as beta sub-unit of FSH. It does not cross react with the alpha sub-unit. Follicle stimulating hormone (FSH) is a hormone synthesized and secreted by gonadotrophs in the anterior pituitary gland. In the ovary, FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows, it releases inhibin, which deactivates the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testis and is critical for spermatogenesis. FSH and LH act synergistically in reproduction. FSH is a useful marker in the classification of pituitary tumors and the study of pituitary disease. |
Synonyms | Follicle stimulating hormone beta polypeptide, Follicle stimulating hormone beta subunit, Follitropin beta chain, Follitropin subunit beta, FSH-B, FSH-beta, FSHB, FSHbeta |
Host | Mouse |
Clonality | Monoclonal |
Clone | FSHb/1062 |
Immunogen | Recombinant hFSH beta sub-unit |
Isotype | IgG1, kappa |
Reactivity | Human |
Applications | FC, IF, IHC |
Form | 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
Gene Id | 2488 |
Uniprot | P01225 |
Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
References | Schmidt M et al. Pathol Res Pract. 2001;197(10):663-9La Rosa S et al. Virchows Arch. 2000 Sep;437(3):264-9Zheng W et al. Gynecol Oncol. 2000 jan;76(1):80- |
Supplier | ARP |
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