| Product Name | Anti-GLIS3 Antibody [PCRP-GLIS3-1B11] |
|---|---|
| Description | Mouse monoclonal [PCRP-GLIS3-1B11] antibody to GLIS3. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | PCRP-GLIS3-1B11 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant full-length human GLIS3 protein. |
| Isotype | IgG1 |
| Molecular Weight | 84 kDa |
| Target | GLIS3 |
| Specificity | GLIS3 is a member of the GLI similar zinc finger protein family, and encodes a nuclear protein with five C2H2 type zinc finger domains. It functions as both an activator and repressor of transcription, and is specifically involved in the development of pancreatic beta cells, thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full length nature of only two have been determined. |
| Reactivity | Human |
| Applications | ELISA, FC, IP |
| Working Dilutions | Flow Cytometry: 1-2 µg/million cells, IP: 1-2µg / 100-500µg proteins |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide. |
| Concentration | 200 µg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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