| Product Name | Anti-GLUT1 Antibody [GLUT1/3132R] - BSA and Azide free |
|---|---|
| Description | Recombinant rabbit monoclonal [GLUT1/3132R] antibody to GLUT1. |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | GLUT1/3132R |
| Conjugate | Unconjugated |
| Immunogen | Recombinant fragment, around amino acids 203-305, of human GLUT1 protein. The exact sequence is proprietary. |
| Isotype | IgG |
| Molecular Weight | 55 kDa |
| Target | GLUT1 |
| Specificity | This antibody recognizes a protein of 55kDa, which is identified as GLUT-1. Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designated as Glut-1 to Glut-12. Glut-1 is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut-1 is expressed at variable levels in many human tissues. Overexpression of Glut-1 has been linked to tumor progression or poor survival of patients with carcinomas of the colon, breast, cervical, lung, bladder and mesothelioma. Glut-1 is a sensitive and specific marker for the differentiation of malignant mesothelioma (positive) from reactive mesothelium (negative). |
| Reactivity | Human |
| Applications | ELISA, FC, IHC-P |
| Working Dilutions | ELISA: 1-2 µg/ml, Flow Cytometry: 1-2 µg/million cells, IHC-P: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free. |
| Concentration | 1 mg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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