| Product Name | Anti-GM-CSF Antibody [E04-5B11] (Biotin) |
|---|---|
| Description | Mouse monoclonal [E04-5B11] antibody to GM-CSF (Biotin). |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | E04-5B11 |
| Conjugate | Biotin |
| Immunogen | E. coli derived recombinant human GM-CSF (Ala18-Glu144). |
| Isotype | IgG1 |
| Target | GM-CSF |
| Specificity | This antibody recognises Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) also known as colony stimulating factor 2. GM-CSF is a cytokine and acts as a hematopoietic grown factor and immune modulator of various immune cells. It is produced by immune cells including T cells and macrophages as well as endothelial and fibroblast cells. GM-CSF has various functions such as roles in recruiting circulating neutrophils, monocytes and lymphocytes. It is also involved in the maturation and activation of neutrophils and macrophages to induce microbial activity and the production of cytokines. GM-CSF elicits these functions through signaling via its receptor GM-CSFR to activate NF-kappaB or STAT5 signaling pathways. The biotinylated Mouse anti Human GM-CSF antibody, clone E04-5B11 (MCA6231B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human GM-CSF antibody, clone E01-1B6 (MCA6230GA) as the capture antibody. |
| Reactivity | Human |
| Applications | ELISA |
| Working Dilutions | ELISA: 1 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide. |
| Concentration | 100 µg/ml |
| Storage | Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light. |
| Supplier | Antibodies.com |
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