| Product Name | Anti-HIF-1 beta Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to HIF-1 beta. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Recombinant human ARNT. |
| Isotype | IgG |
| Molecular Weight | Approximately 87 kDa in cell lysates under reducing conditions. Rabbit anti ARNT antibody also appears to detect a modified form of ARNT at a higher molecular weight. |
| Target | HIF-1 beta |
| Specificity | This antibody recognises aryl hydrocarbon receptor nuclear translocator (encoded by the gene ARNT), also known as hypoxia-inducible factor 1-beta (HIF1-beta) or bHLHe2. ARNT is a member of the bHLH PAS (basic helix-loop-helix Per-ARNT-Sim) family of transcription factors. ARNT forms complexes with either hypoxia-inducible factor 1-alpha (HIF-1 alpha) or aryl hydrocarbon receptor (AhR), ARNT is involved in the adaptive response to stress caused by dioxins and hypoxia. |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Working Dilutions | WB: 1:500 - 1:2,000 |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide. |
| Concentration | Lot Specific |
| Storage | Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Supplier | Antibodies.com |
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