| Product Name | Anti-Histamine Polyclonal Antibody |
|---|---|
| Description | Histamine is an organic nitrogen compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. Histamine triggers the inflammatory response. As part of an immune response to foreign pathogens, histamine is produced by basophils and by mast cells found in nearby connective tissues. Histamine increases the permeability of the capillaries to white blood cells and some proteins, to allow them to engage pathogens in the infected tissues. |
| Clonality | Polyclonal |
| Immunogen | Histamine conjugated to BSA |
| Specificity | Absorption with 10-100 ?g histamine per ml diluted antiserum abolishes the staining, while noradrenaline, 5-HT, VIP, glucagons and histidine do not. |
| Reactivity | Human, Mouse, Rat, Mammal |
| Applications | IHC |
| Form | Serum containing 0.1% sodium azide |
| Storage | 2-8C for immediate use, or at -2°C (aliquot) |
| References | Hakansson R et al. (1986) Histochemistry 86: 5-17Johansson O et al. (1992) Histochem J 24: 283-287Axelson J et al. (1990) Gastroenterology 99: 635-640 |
| Background | Histamine is an organic nitrogen compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. Histamine triggers the inflammatory response. As part of an immune response to foreign pathogens, histamine is produced by basophils and by mast cells found in nearby connective tissues. Histamine increases the permeability of the capillaries to white blood cells and some proteins, to allow them to engage pathogens in the infected tissues. |
| Supplier | ARP |
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