| Product Name | Anti-HLA Aw32 + HLA A25 Antibody [SPM417] - BSA and Azide free |
|---|---|
| Description | Mouse monoclonal [SPM417] antibody to HLA Aw32 + HLA A25. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | SPM417 |
| Conjugate | Unconjugated |
| Immunogen | Normal human peripheral blood lymphocytes of phenotype A1, Aw32, B7, B37, Cw-, Cw-, DR2, DRw10. |
| Isotype | IgG2a |
| Target | HLA Aw32 + HLA A25 |
| Specificity | This antibody reacts with cells bearing HLA-A25 or HLA-Aw32 antigens. In addition, a reaction was observed with a cell of phenotype A2, Aw31; B17, Bw49. HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. HLA system comprises closely linked genes controlling highly polymorphic proteins involved in the presentation of peptides to the T-cell receptor, inhibition of NK cell cytotoxicity, and rejection of tissue allotransplantation. Specific alleles at HLA loci are associated with diseases. This antibody is specifically applicable for typing peripheral T cells for the antigens HLA-A25 and HLA-Aw32. |
| Reactivity | Human |
| Applications | FC, IF, IHC-P |
| Working Dilutions | Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free. |
| Concentration | 1 mg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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