| Product Name | Anti-HSP27 Antibody [rHSPB1/7298] - BSA and Azide free |
|---|---|
| Description | Recombinant mouse monoclonal [rHSPB1/7298] antibody to HSP27. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | rHSPB1/7298 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant human full-length HSP27 protein. |
| Isotype | IgG1 |
| Molecular Weight | 27 kDa |
| Target | HSP27 |
| Specificity | HSP27, also referred to as the Estrogen-Regulated 24K protein and HSP28, is one of several small heat shock proteins produced by all organisms studied. HSP27 synthesis is induced by elevated temperature, as well as by estrogen in hormone responsive cells. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSPs and mammalian -crystalline lens protein. Because of the estrogen responsive nature of HSP27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. Therefore, HSP27 may be useful in classifying various hormone sensitive tumors. |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free. |
| Concentration | 1 mg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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