Product Name | Anti-Human CD3 Monoclonal Antibody (APC Conjugated) |
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Description | The HIT3a monoclonal antibody reacts with human CD3e, a 20 kDa subunit of the TCR complex. Along with the other CD3 subunits _ and _, the _ chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR with HIT3a initiates an intracellular biochemical pathway resulting in cellular activation and proliferation. |
Host | Mouse |
Clone | HIT3a |
Isotype | Mouse IgG2a |
Reactivity | Human |
Applications | FCM |
Form | PBS with 0.09% NaN3, 0.2% BSA, PH7.2 |
Background | The HIT3a monoclonal antibody reacts with human CD3e, a 20 kDa subunit of the TCR complex. Along with the other CD3 subunits _ and _, the _ chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR with HIT3a initiates an intracellular biochemical pathway resulting in cellular activation and proliferation. |
Supplier | Elabscience |
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