| Product Name | Anti-ICAM1 Antibody [84H10] |
|---|---|
| Description | Mouse monoclonal [84H10] antibody to ICAM1. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 84H10 |
| Conjugate | Unconjugated |
| Immunogen | K562 cell line. |
| Isotype | IgG1 |
| Target | ICAM1 |
| Specificity | This antibody recognises the D1 domain of ICAM-1.It reacts with the ICAM-1 antigen found in low levels on lymphocytes and strongly expressed on monocytes and granulocytes. This molecule is inducible to high levels by mitogenic lectins on lymphocytes and by IL-1 beta or IFN gamma on other cell types such as fibroblasts and endothelial cells. Mouse anti Human CD54 antibody, clone 84H10 detects an antigen of ~90 kDa. Mouse anti Human CD54 antibody, clone 84H10 has been reported to block ICAM1 mediated cellular adhesion and block binding of LFA-1 and P. falciparum to ICAM-1. Mouse anti Human CD54 antibody, clone 84H10 is routinely tested in flow cytometry on rat splenocytes. |
| Reactivity | Canine, Human |
| Applications | IHC-Fr, ELISA, FA, FC, IP |
| Working Dilutions | Flow Cytometry: Neat - 1:10, IHC-Fr 2: 1:20 - 1:50, IP: 5µg per 107 cells, Use 10µl of the suggested working dilution to label 106 cells in 100µl. |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide. |
| Concentration | 1 mg/ml |
| Storage | Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. |
| Supplier | Antibodies.com |
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