| Product Name | Anti-ICAM1 Antibody (Biotin) - BSA and Azide free |
|---|---|
| Description | Rabbit polyclonal antibody to ICAM1 (Biotin). |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Biotin |
| Immunogen | Recombinant human CD54. |
| Isotype | IgG |
| Target | ICAM1 |
| Specificity | This antibody recognises human CD54, otherwise known as Intercellular adhesion molecule 1 or ICAM-1. CD54 is a 532 amino acid single pass type I membrane glycoprotein containing five Ig-like C2-type domains. CD54 is widely expressed and acts as a ligand for the leukocyte integrin LFA-1 (CD11a/CD18) and Mac-1 integrins, it is the major receptor for human rhinovirus. CD54 is highly expressed on activated endothelial cells (Favoloro 1993) and plays a role in transendothelial cell migration to sites of acute inflammation, functioning primarily as an adhesion molecule between endothelial cells and leucocytes, following injury or stress. Levels of soluble CD54 in serum or urine , can be potentially used as an indication of infection, inflammation and certain tumour, and as a target for immunosuppression in transplantation. |
| Reactivity | Human |
| Applications | ELISA, WB |
| Working Dilutions | ELISA: 0.25 - 1 µg/ml, WB: 0.1 - 0.2 µg/ml |
| Form | Lyophilized |
| Diluent Buffer | Supplied in Phosphate Buffered Saline. |
| Concentration | 100 µg/ml after reconstitution. |
| Storage | Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Supplier | Antibodies.com |
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