| Product Name | Anti-IGF2 Antibody - BSA and Azide free |
|---|---|
| Description | Rabbit polyclonal antibody to IGF2. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Recombinant human IGF-II. |
| Isotype | IgG |
| Target | IGF2 |
| Specificity | This antibody recognises human IGF-II (Insulin-like Growth Factor II), a 67 amino acid mitogenic polypeptide and member of the Insulin gene family, synthesized by various foetal tissues during prenatal development, under the influence of placental lactogen.IGF-II is a growth factor which exhibits both paracrine and autocrine properties and signals by binding to the type 1 and type 2 insulin-like growth factor receptors (type 1 IGFR and type 2 IGFR), and also to the insulin receptor (IR). The availability of IGF-II is dependent upon its attachment to, and release from, various IGF binding proteins (IGFBPs), a relationship which has been investigated in breast cancer research. |
| Reactivity | Human |
| Applications | ELISA, FA, IHC-P, WB |
| Working Dilutions | ELISA: 0.5 - 2 µg/ml, Functional Assays: 3.1 - 4.6 µg/ml, WB: 0.1 - 0.2 µg/ml |
| Form | Lyophilized |
| Diluent Buffer | Supplied in Phosphate Buffered Saline. |
| Concentration | 1 mg/ml after reconstitution. |
| Storage | Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Supplier | Antibodies.com |
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