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|Product Name||Anti-IGLL1 (clone AT1G4)|
|Description||IGLL1 (Immunoglobulin lambda-like polypeptide 1) and VpreB comprise the surrogate light chain of the pre-B cell receptor complex. The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. Expression of IGLL1 is highest in liver, preB lymphocytes and bone marrow, the major source of B cell precursors.|
|Applications||Dot blot, ELISA, WB|
|Clone||AT1G4. Anti-human IGLL1 mAb, clone AT1G4, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human IGLL1 protein.|
|Form||Purified, in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.02% Sodium Azide.|
|Immunogen||Recombinant human IGLL1 (38-213aa) purified from E. coli|
|References||Bauer. S.R., et al. (1988) Immunogenetics 28(5): 328€“333 Schiff. C., et al (1989) Eur J Immunol 19(10): 1873€“1878Minegishi. Y., et al. (1998) J Exp Med 187: 71-77|
|Storage||Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.|
|Synonyms||Immunoglobulin lambda-like polypeptide 1, 14.1, AGM2, CD179b, IGL1, IGL5, IGLJ14.1, IGLL, IGO, IGVPB, VPREB2|
|Working Dilutions||Optimal dilution should be performed by user.|
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