| Product Name | Anti-Influenza A H3N2 Antibody |
|---|---|
| Description | Goat polyclonal antibody to Influenza A H3N2. |
| Host | Goat |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Influenza A strain: Texas 1/77 (H3N2). |
| Isotype | IgG |
| Target | Influenza A H3N2 |
| Specificity | This antibody recognises influenza AH3N2 by haemagglutination inhibition.Goat anti Influenza A H3N2 antibody does not react with influenza B, RSV, Para 1-3 or Adenovirus, but may react with proteins present on uninfected chicken cells.Influenza type A viruses are divided into subtypes based on the antigenic differences of two viral surface proteins, hemagglutinin (H) and neuraminidase (N). On infection of the respiratory tract, the hemagglutinin molecule binds to sialic acid-containing receptors on the epithelial cells resulting in endocytosis. Once the virus has been engulfed, the hemagglutinin allows the viral membrane to fuse with the endosomal membrane. Neuraminidase functions to aid viral release from host cells by cleaving terminal sialic acid residues from carbohydrate moieties on the cell surface.Subtype antigenic variations result from a process known as antigenic drift whereby these surface proteins constantly mutate in order to evade the host immune response. |
| Reactivity | Virus |
| Applications | HAI, IF |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide. |
| Concentration | 1 mg/ml |
| Storage | Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. |
| Supplier | Antibodies.com |
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