| Product Name | Anti-Interferon regulatory factor-3 (clone 3F10 ) |
|---|---|
| Description | Members of the Interferon regulatory factor (IRF) family regulate gene expression critical to immune response, hemopoiesis, and proliferation. IRF-3 is a member of the IRF family, and is distinct from other family members. Its transcriptional activity is regulated solely by posttranslational modifications. It plays a crucial role in activation of innate immunity and inflammation in response to viral infection. |
| Synonyms | IRF3, Interferon regulatory factor-3, IRF-3, Interferon regulatory factor 3, IRF 3. |
| Host | Mouse |
| Clone | 3F10. Anti-human IRF-3 mAb, clone 3F10, is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human IRF-3 protein. |
| Immunogen | Recombinant human IRF-3(108-166aa) purified from E. coli |
| Isotype | IgG1,K |
| Reactivity | Human, Mouse |
| Applications | ELISA, IF, IP, WB, Dot Blot |
| Form | Purified, in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.01% Sodium Azide. |
| Storage | Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles. |
| References | DeFilippis VR et al.,(2006) J Virol 80(2):1032-1037 Pietila TE et al.,(2007) J Immunol 178(1):253-261 |
| Supplier | ARP |
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