Anti-Kappa Light Chain (B-Cell Marker), Monoclonal Antibody
| Product Name | Anti-Kappa Light Chain (B-Cell Marker), Monoclonal Antibody |
|---|---|
| Description | This monoclonal antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant. |
| Synonyms | HCAK1, Ig Kappa Chain C Region, IGKC, Immunoglobulin KM |
| Host | Mouse |
| Clone | HP6053 |
| Immunogen | Purified human Ig kappa chain |
| Isotype | IgG1, kappa |
| Reactivity | Human |
| Applications | FC, IHC, WB |
| Form | 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Gene Id | 3514 |
| Uniprot | P01601 & P01834 |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | Takahashi H et. al. Pathol Res Prac 189:300-311 (1993).2. Momose H et. al. Hum Pathol. 23:1115-1119 (1992) |
| Supplier | ARP |
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