| Product Name | Anti-Keratin 77 Antibody [rKRTL/8751] - BSA and Azide free |
|---|---|
| Description | Recombinant mouse monoclonal [rKRTL/8751] antibody to Keratin 77. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | rKRTL/8751 |
| Conjugate | Unconjugated |
| Immunogen | Human epidermal keratin. |
| Isotype | IgG1 |
| Molecular Weight | 40-56.5 kDa |
| Target | Keratin 77 |
| Specificity | This MAb recognizes the 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50 , 48, 46, 45, and 40kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. |
| Reactivity | Reptile, Gallus, Monkey, Bovine, Canine, Human, Mouse, Rabbit, Rat |
| Applications | IHC-P |
| Working Dilutions | IHC: 0.5-1 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free. |
| Concentration | 1 mg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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