Anti-Lea (ISBT No 7001)/CD174 Antigen Monoclonal Antibody, PE

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08-9422-4
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Product Name Anti-Lea (ISBT No 7001)/CD174 Antigen Monoclonal Antibody, PE
Description Mouse monoclonal antibody to human Lea (ISBT No. 7001)/CD174 Culture supernatant. The Lea antigen is the carbohydrate structure: Gal 1-3 (Fuc alpha1-4) GlcNAc 1-R or monofucosylated Type I chain. Depending on the tissue of origin, the antigen is found on cell surfaces and on glycoproteins in exocrine secretions of individuå_als of genotype se/se, Le/-. Also found in circulating glycosphingolipids which are passively adsorbed to the surface of circulating cells. .
Synonyms Lewis a antigen, Lewis a protein, CD174
Clonality Monoclonal
Clone BRIC 87
Immunogen Lea (ISBT No. 7001)/CD174. BRIC 87 was made in response to human erythrocytes.
Isotype Mouse IgM kappa light chain
Reactivity Human
Applications FC, IF
Form PE-conjugate, in PBS buffer, pH 7.2 containing 0.1% sodium azide, 1% BSA
Storage 2-8C, do not freeze
References 1. Oriol, R., et al. (1986) Vox Sang. 51, 161-171 (review) 2. Chester, M.A. et al. (Eds.) (1990) Proceedings of the Second International Workshop and Symposium on Monoclonal Antibodies against Human Blood Cells and Related Antigens, Lund, 1990. 3. Henry SM et al. (1994) Glycoconjugate J. 11: 600-607
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