Anti-MAPK1 (AT1A4)

Antibodies, Monoclonal Antibodies
Questions? Contact Us
More Information
Product Name Anti-MAPK1 (AT1A4)
Description Mitogen-activated protein kinases (MAPKs) are reported to be critical regulatory factors for the growth andmigration of various cell types including vascular smooth muscle cells (VSMCs). It has also been reported that the activation of the MAP kinase family, extracellular signal regulated kinases 1/2 (ERK1/2), and c-Jun N-terminal kinase (JNK) via Src activation is important for AII-induced migration of VSMCs. MAPKs are intracellular signal-transduction pathways that have been shown to play a central role in the development of injury following ischemia in the brain and heart. MAPKs regulate gene expression, which is important in cell injury/repair and proliferation/differentiation.
Reactivity Human
Applications Dot blot, ELISA, IF, WB
Clone AT1A4. Anti-human MAPK1 mAb, clone AT1A4, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human MAPK1 protein.
Concentration 0.1 mg/ml
Form Purified, in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide
Species Mouse
Host Mouse
Isotype K, IgG2b
Immunogen Recombinant human MAPK1 (1-360) purified from E.coli
Interest Fields Cancer
NCBI Number NP_620407
References Le A, et al. (2010) Proc Natl Acad Sci U S A, 107(5):2037-42. Gesslein B, et al. (2010) Mol Vis,16:392-407. Lai EW, et al. (2004) J Invest Surg, 17:45-53.
Storage Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
Synonyms ERK, ERK2, ERT1, MAPK2, p38, p40, p41, p41mapk, P42MAPK, PRKM1, PRKM2, Mitogen-activated protein kinase 1 MAP kinase 2, MAPK 2, ERK 2, Extracellular Signal Regulated Kinase 2, MAPK 1.
Working Dilutions Optimal dilution should be performed by user.

All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.

Customers Also Viewed
  1. Anti-ERVW-1 Polyclonal Antibody
    Anti-ERVW-1 Polyclonal An...
    Rabbit IgG polyclona...
    Mouse, Rat, Reacts w...
  2. BAG1, 1-230aa, Human
    BAG1, 1-230aa, Human

Hi, have questions?

An ARP Customer Service Representative is happy to help!

or Call (800) 832-2611