| Product Name | Anti-MLST8 Polyclonal Antibody |
|---|---|
| Description | Cell growth is a fundamental biological process whereby cells accumulate mass and increase in size. The mammalian Target of Rapamycin (mTOR) pathway regulates growth by coordinating energy and nutrient signals with growth factor-derived signals. mTOR is a large protein kinase with two different complexes. One complex contains mTOR, G_L, and raptor, which is a target of rapamycin. The other complex, insensitive to rapamycin, includes mTOR, G_L, and rictor. G_L associates with the kinase domain of mTOR and stimulates mTOR kinase activity. A reduction in G_L expression has been shown to decrease in vivo phosphorylation of S6K1. |
| Host | Rabbit |
| Immunogen | Recombinant protein of human MLST8 |
| Isotype | IgG |
| Reactivity | Human |
| Applications | ELISA, IHC, WB |
| Form | Liquid, in PBS with 0.02% sodium azide, 50% glycerol, pH 7.3. |
| Storage | Store at -20C or -80C. Avoid repeated freeze/thaw cycles. |
| Background | Cell growth is a fundamental biological process whereby cells accumulate mass and increase in size. The mammalian Target of Rapamycin (mTOR) pathway regulates growth by coordinating energy and nutrient signals with growth factor-derived signals. mTOR is a large protein kinase with two different complexes. One complex contains mTOR, G_L, and raptor, which is a target of rapamycin. The other complex, insensitive to rapamycin, includes mTOR, G_L, and rictor. G_L associates with the kinase domain of mTOR and stimulates mTOR kinase activity. A reduction in G_L expression has been shown to decrease in vivo phosphorylation of S6K1. |
| Supplier | Cusabio |
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