Anti-Mouse CD11b In Vivo Antibody - Low Endotoxin (M1/70)

Category: Antibodies
Catalog
ICH1049
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Product Name Anti-Mouse CD11b In Vivo Antibody - Low Endotoxin (M1/70)
Synonyms Integrin alpha-M, Itgam, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1
Host Rat
Clonality Monoclonal
Clone M1/70
Immunogen B10 mouse spleen cells enriched for T cells
Isotype Rat IgG2b
Target CD11b
Specificity Anti-CD11b In Vivo Antibody - Low Endotoxin (M1/70) recognizes the (Mr 170 kD) alpha m subunit of Mac-1 (CD11b/CD18, alpha m beta 2 integrin), the mouse macrophage-granulocyte specific antigen. Mac-1 is a macrophage differentiation antigen associated with type three complement receptor and mediates adhesion to CD54 (ICAM-1).
Reactivity Mouse
Applications IHC-Fr, FA, FC, ICC, IP, MC, WB
Diluent Buffer 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Reconstitution Functional Assay: Activation of mouse peritoneal macrophages Each investigator should determine their own optimal working dilution for specific applications.
Concentration 0.5 mg/ml
Purity >95% by SDS-PAGE and HPLC
Uniprot P05555
Storage anti-CD11b In Vivo Antibody - Low Endotoxin (M1/70) is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Notes Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Supplier Ichorbio

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