| Product Name | Anti-Mouse CD16/32 Monoclonal Antibody (FITC conjugated) |
|---|---|
| Description | The 2.4G2 antibody reacts specifically with a common nonpolymorphic epitope on the extracellular domains of the mouse Fc_III and Fc_II receptors. It has also been reported to bind the Fc_I receptor (CD64) via its Fc domain. 2.4G2 mAb blocks non-antigen-specific binding of immunoglobulins to the Fc_III and Fc_II, and possibly Fc_I, receptors in vitro and in vivo. CD16 and/or CD32 are expressed on natural killer cells, monocytes, macrophages, dendritic cells (at low levels), Kupffer cells, granulocytes, mast cells, B lymphocytes, immature thymocytes, and some activated mature T lymphocytes. |
| Synonyms | Fc_RII/III |
| Host | Rat |
| Clone | 2.4G2 |
| Isotype | Rat IgG2b |
| Reactivity | Mouse |
| Applications | FCM |
| Form | PBS with 0.09% NaN3, 0.2% BSA, PH7.2 |
| Background | The 2.4G2 antibody reacts specifically with a common nonpolymorphic epitope on the extracellular domains of the mouse Fc_III and Fc_II receptors. It has also been reported to bind the Fc_I receptor (CD64) via its Fc domain. 2.4G2 mAb blocks non-antigen-specific binding of immunoglobulins to the Fc_III and Fc_II, and possibly Fc_I, receptors in vitro and in vivo. CD16 and/or CD32 are expressed on natural killer cells, monocytes, macrophages, dendritic cells (at low levels), Kupffer cells, granulocytes, mast cells, B lymphocytes, immature thymocytes, and some activated mature T lymphocytes. |
| Supplier | Elabscience |
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