| Product Name | Anti-Mouse CD49d Monoclonal Antibody (PE/Cy5 conjugated) |
|---|---|
| Description | CD49d is a 150 kD glycoprotein, also known as _4 integrin or VLA-4 _ chain. It is a member of the integrin family, expressed on T and B cells, monocytes, eosinophils, basophils, mast cells, thymocytes, NK cells, and dendritic cells. CD49d is a heterodimer expressed with either of two _ chains, _1 (CD29) or _7, to form the VLA-4 (integrin _4_1) or LPAM-1 (integrin _4_7) complexes. CD49d plays a critical role in both adhesion and T cell costimulation. The primary ligands for CD49d are VCAM-1, MAdCAM-1, and fibronectin. |
| Synonyms | Integrin _4 |
| Host | Rat |
| Clone | PS/2 |
| Isotype | Rat IgG2b |
| Reactivity | Mouse |
| Applications | FCM |
| Form | PBS with 0.09% NaN3, 0.2% BSA, PH7.2 |
| Background | CD49d is a 150 kD glycoprotein, also known as _4 integrin or VLA-4 _ chain. It is a member of the integrin family, expressed on T and B cells, monocytes, eosinophils, basophils, mast cells, thymocytes, NK cells, and dendritic cells. CD49d is a heterodimer expressed with either of two _ chains, _1 (CD29) or _7, to form the VLA-4 (integrin _4_1) or LPAM-1 (integrin _4_7) complexes. CD49d plays a critical role in both adhesion and T cell costimulation. The primary ligands for CD49d are VCAM-1, MAdCAM-1, and fibronectin. |
| Supplier | Elabscience |
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