Anti-Mouse LPAM-1 (Integrin _4_7) Monoclonal Antibody (PE/Cy5 conjugated)
| Product Name | Anti-Mouse LPAM-1 (Integrin _4_7) Monoclonal Antibody (PE/Cy5 conjugated) |
|---|---|
| Description | DATK32 antibody is specific for a combinatorial determinate of integrin _4_7complex. Integrin _4_7 is composed of a 150 kD (_4 or CD49d) and a 130 kD (_7) heterodimer, also known as CD49d/_7 or LPAM-1. Belonging to the Ig superfamily, it is found on the majority of peripheral lymphocytes and subsets of thymocytes and bone marrow cells (including mast cell progenitors). Integrin _4_7 binds its ligands, VCAM-1 (CD106), MAdCAM-1 and fibronectin, and plays an important role in lymphocytes adhesion and the direction of migration of blood lymphocytes to the intestine and associated lymphoid tissues. |
| Host | Rat |
| Clone | DATK32 |
| Isotype | Rat IgG2a |
| Reactivity | Mouse |
| Applications | FCM |
| Form | PBS with 0.09% NaN3, 0.2% BSA, PH7.2 |
| Background | DATK32 antibody is specific for a combinatorial determinate of integrin _4_7complex. Integrin _4_7 is composed of a 150 kD (_4 or CD49d) and a 130 kD (_7) heterodimer, also known as CD49d/_7 or LPAM-1. Belonging to the Ig superfamily, it is found on the majority of peripheral lymphocytes and subsets of thymocytes and bone marrow cells (including mast cell progenitors). Integrin _4_7 binds its ligands, VCAM-1 (CD106), MAdCAM-1 and fibronectin, and plays an important role in lymphocytes adhesion and the direction of migration of blood lymphocytes to the intestine and associated lymphoid tissues. |
| Supplier | Elabscience |
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