Anti-MUC5AC (Mucin 5AC / Gastric Mucin), Monoclonal Antibody
| Product Name | Anti-MUC5AC (Mucin 5AC / Gastric Mucin), Monoclonal Antibody |
|---|---|
| Description | This monoclonal antibody recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC)._Its epitope is located in the peptide core of MUC5AC. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. monoclonal antibody 1-13M1 pairs with monoclonal antibody 9-13M1 to measure MUC5AC protein by ELISA. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas. |
| Synonyms | Apomucin Major Airway Glycoprotein, Mucin 5 subtype AC tracheobronchial, Mucin 5 Subtypes A And C, Mucin 5AC oligomeric mucus/gel forming, Tracheobronchial Mucin (TBM) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1-13M1 |
| Immunogen | M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient |
| Isotype | IgG1, kappa |
| Reactivity | Gallus, Bovine, Feline, Human, Mouse, Primate, Rabbit, Rat |
| Applications | FC, IF, IHC |
| Form | 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Gene Id | 4586 |
| Uniprot | P98088 |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | Cancer Res.46: 3983-3989 (1986).Biochem. J. 254: 185-193 (1988).Int. J. Cancer 47: 304-310 (1991).J. Immunol. Methods 149: 105-113 (1992 |
| Supplier | ARP |
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