| Product Name | Anti-MyoD1 (Rhabdomyosarcoma Marker), Monoclonal Antibody |
|---|---|
| Description | Recognizes a phosphor-protein of 45kDa, identified as MyoD1. This monoclonal antibody does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas. |
| Synonyms | bHLHc1, Class C basic helix-loop-helix protein 1, Myoblast determination protein 1, Myogenic differentiation 1, Myogenic factor 3 (Myf-3), Myogenin D1, PUM |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | MYD712 |
| Immunogen | Recombinant human MyoD1 protein |
| Isotype | IgG1, kappa |
| Reactivity | Human |
| Applications | FC, IF, IHC |
| Form | 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml. |
| Gene Id | 4654 |
| Uniprot | P15172 |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | Thulasi R et. al. Cell Growth and Differentiation, 1996, 7(4):531-41.Wesche WA et. al. American Journal of Surgical Pathology, 1995, 19(3):261-9.Parham DM et. al. Acta Neuropathologica, 1994, 87:605-11. |
| Supplier | ARP |
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