| Product Name | Anti-NCR1 Antibody [AKS1] - BSA and Azide free |
|---|---|
| Description | Mouse monoclonal [AKS1] antibody to NCR1. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | AKS1 |
| Conjugate | Unconjugated |
| Immunogen | Fusion protein consisting of the extracellular region of bovine CD335. |
| Isotype | IgG1 |
| Target | NCR1 |
| Specificity | This antibody recognises bovine CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1. CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor. CD335 is expressed by human natural killer cells. The bovine homologue is expressed on bovine NK cells and no expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes.Clone AKS1 is reported to activate lysis of FcgammaR-expressing cell line P815, by IL-2 activated NKp46+ cells. |
| Reactivity | Bison, Bovine |
| Applications | FA, FC, IF, WB |
| Working Dilutions | Flow Cytometry: 1:50 - 1:200, Use 10µl of the suggested working dilution to label 106 cells in 100µl |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline. |
| Concentration | 1 mg/ml |
| Storage | Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Supplier | Antibodies.com |
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