| Product Name | Anti-Neurotensin Polyclonal Antibody |
|---|---|
| Description | This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. |
| Synonyms | NTS, NN, NT, NT/N, NTS1, NMN-125 |
| Clonality | Polyclonal |
| Immunogen | Synthetic bovine neurotensin |
| Specificity | The antibody can be used to discriminate tumors derived from endocrine cells of the lieum and adrenal medulla. |
| Reactivity | Amphibian, Bovine, Feline, Human, Rat |
| Applications | IHC |
| Form | Serum containing 0.1% sodium azide |
| Storage | 2-8C for immediate use, or at -2°C (aliquot) |
| References | Maake C et al. (1999) Cell Tissue Res 297: 91-101Karila P et al. (1995) Regul Peptides 58: 25-29Larsson L et al. (1990) Arch A Pathol Anat 416: 465-475 |
| Background | This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. |
| Supplier | ARP |
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