Anti-Nitric Oxide Synthase (C-terminus) Polyclonal Antibody

Category: Antibodies
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03-16059
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Product Name Anti-Nitric Oxide Synthase (C-terminus) Polyclonal Antibody
Description Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms NOS
Clonality Polyclonal
Immunogen Synthetic peptide from C-terminal of rat cerebellar NO-Synthase conjugated to BSA
Specificity The antiserum was raised against a synthetic peptide of rat cerebellar NOS, that shows no homology with other related proteins. Absorption with 10-100 ?g immunogen per ml diluted antiserum abolishes the staining.
Reactivity Canine, Feline, Human, Rat
Applications IF
Form Serum containing 0.1% sodium azide
Storage 2-8C for immediate use, or at -2°C (aliquot)
References Alm, P.. et al. (1993) Acta Physiol Scand. 148: 421-429Ekblad, E. et al. (1994) Neuroscience 63: 233-248Ny, L. et al. (1996) Brit. J Pharmacol 118: 392-399Ny, L. et al. (1997) J Auton Nerv Syst. 65: 49-56
Background Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene.
Supplier ARP

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