| Product Name | Anti-NR2F6 Monoclonal Antibody |
|---|---|
| Description | NR2F6 (Nuclear receptor subfamily 2 group F member 6), also known as EAR2 or ERBAL2, is a transcription factor involved in modulation of hormonal responses. NR2F6 represses e.g. transcription of the oxytocin-neurophysin gene, renin gene, lutropin-choriogonadotropic hormone receptor gene, and the thyroid hormone receptor gene. In the immune system, NR2F6 affects IL-17 expression in the Th-17 cells, thus also the balance between immunological tolerance and autoimmunity. |
| Clone | EM-51 |
| Immunogen | Recombinant human NR2F6 protein expressed in E. coli |
| Isotype | IgG2a |
| Specificity | The mouse monoclonal antibody EM-51 recognizes NR2F6, a transcriptional repressor expressed mainly in the heart, placenta, liver, skeletal muscle, kidney and pancreas, but also e.g. in T cell subpopulations. |
| Reactivity | Human |
| Applications | WB |
| Form | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage | Store at 2-8°C. Do not freeze. |
| Background | NR2F6 (Nuclear receptor subfamily 2 group F member 6), also known as EAR2 or ERBAL2, is a transcription factor involved in modulation of hormonal responses. NR2F6 represses e.g. transcription of the oxytocin-neurophysin gene, renin gene, lutropin-choriogonadotropic hormone receptor gene, and the thyroid hormone receptor gene. In the immune system, NR2F6 affects IL-17 expression in the Th-17 cells, thus also the balance between immunological tolerance and autoimmunity. |
| Supplier | Exbio |
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