Anti-NSE (clone AT17D10)

Antibodies, Monoclonal Antibodies
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Product Name Anti-NSE (clone AT17D10)
Description Neuron-specific enolase (NSE) is a glycolytic isoenzyme which is located in central and peripheral neurons and neuroendocrine cells. This enzyme is released into the CSF when neural tissue is injured. Neoplasms derived from neural or neuroendocrine tissue may release NSE into the blood. NSE is a useful substance that has been detected in patients with certain tumors, namely: neuroblastoma, small cell lung cancer, medullary thyroid cancer, carcinoid tumors, pancreatic endocrine tumors, and melanoma.
Reactivity Human
Applications Dot blot, ELISA, WB
Clone Anti-human NSE mAb, clone AT17D10, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human NSE protein.
Concentration 0.1mg/ml
Form Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.02% Sodium Azide.
Species Mouse
Host Mouse
Isotype K, IgG2b
Immunogen Recombinant human NSE (1-434aa) purified from E. coli
NCBI Number NP_001966
References Oliva D, Calì L, Feo S, Giallongo A (1991). Genomics 10 (1): 157€“65.Craig SP, Day IN, Thompson RJ, Craig IW (1991). Cytogenet. Cell Genet. 54 (1€“2): 71€“3.McAleese SM, Dunbar B, Fothergill JE, et al. (1989). Eur. J. Biochem. 178 (2): 413€“7.
Storage Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
Synonyms Enolase 2 (gamma, neuronal), ENO2, NSE, Neuron-Specific Enolase, 2 phospho D glycerate hydrolyase, Eno 2, ENOG, Enolase 2 gamma neuronal, Enolase2, Gamma enolase, Neural enolase, Neuron specific enolase, Neuron specific gamma enolase, Neurone specific enolase.
Working Dilutions Optimal dilution should be performed by user.

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