| Product Name | Anti-NSE (clone AT17D10) |
|---|---|
| Description | Neuron-specific enolase (NSE) is a glycolytic isoenzyme which is located in central and peripheral neurons and neuroendocrine cells. This enzyme is released into the CSF when neural tissue is injured. Neoplasms derived from neural or neuroendocrine tissue may release NSE into the blood. NSE is a useful substance that has been detected in patients with certain tumors, namely: neuroblastoma, small cell lung cancer, medullary thyroid cancer, carcinoid tumors, pancreatic endocrine tumors, and melanoma. |
| Synonyms | Enolase 2 (gamma, neuronal), ENO2, NSE, Neuron-Specific Enolase, 2 phospho D glycerate hydrolyase, Eno 2, ENOG, Enolase 2 gamma neuronal, Enolase2, Gamma enolase, Neural enolase, Neuron specific enolase, Neuron specific gamma enolase, Neurone specific enolase. |
| Host | Mouse |
| Clone | Anti-human NSE mAb, clone AT17D10, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human NSE protein. |
| Immunogen | Recombinant human NSE (1-434aa) purified from E. coli |
| Isotype | K,IgG2b |
| Reactivity | Human, Mouse |
| Applications | ELISA, WB, Dot Blot |
| Form | Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.02% Sodium Azide. |
| Storage | Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles. |
| References | Oliva D, Calì L, Feo S, Giallongo A (1991). Genomics 10 (1): 157€“65.Craig SP, Day IN, Thompson RJ, Craig IW (1991). Cytogenet. Cell Genet. 54 (1€“2): 71€“3.McAleese SM, Dunbar B, Fothergill JE, et al. (1989). Eur. J. Biochem. 178 (2): 413€“7. |
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