| Product Name | Anti-Nucleolar Protein xNopp180 Monoclonal Antibody |
|---|---|
| Description | xNopp180 is a constitutively expressed nucleolar component and a specific marker for the dense fibrillar component of the interphase nucleolus. Mouse monoclonal Antibody to Nucleolar Protein xNopp180. |
| Synonyms | p130, nopp130, nopp140, ns5atp13, xNopp180 |
| Clonality | Monoclonal |
| Clone | No-114 |
| Immunogen | Nucleolar fraction prepared from Xenopus laevis oocytes |
| Isotype | IgG1 |
| Specificity | The antibody stains specifically the nucleolus and Cajal bodies in interphase cells. The antigen is a constitutively expressed nucleolar component and a specific marker for the dense fibrillar component of the interphase nucleolus. The protein recognized is a 180 kD polypeptide in Xenopus (xNopp180), homologue to the rat polypeptide (Nopp140). When applied at high concentration to human cells the antibody reacts with a nucleolar component which, however, does not correspond to xNopp180 |
| Reactivity | Amphibian, Gallus, Mouse, Rat |
| Applications | IF, IP, WB |
| Form | Hybridoma culture supernatant |
| Storage | 2-8C |
| References | Schmidt-Zachmann, MS et al. (1984) Exp. Cell Res. 153: 327-346Cairns, C. et al. (1995) J. Cell Sci. 108: 3339-3347Kneissel S et al (2001) Mol. Biol Cell 12: 3904-3918 |
| Background | xNopp180 is a constitutively expressed nucleolar component and a specific marker for the dense fibrillar component of the interphase nucleolus. |
| Supplier | ARP |
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