Anti-Ornithine Decarboxylase-1 (ODC-1), Monoclonal Antibody
| Product Name | Anti-Ornithine Decarboxylase-1 (ODC-1), Monoclonal Antibody |
|---|---|
| Description | Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa. |
| Synonyms | Ornithine decarboxylase structural 1, RNODC |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | SPM565 |
| Immunogen | Recombinant human ODC-1 protein |
| Isotype | IgG1, kappa |
| Reactivity | Human, Rat |
| Applications | FC, IF, IHC, WB |
| Form | 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Gene Id | 4953 |
| Uniprot | P11926 |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | Schipper RG; Rutten RG; Sauerbeck M; Schielen WJ; Adams PJ; Kopitz J; Bohley P; Tesser GI; Verhofstad AA. Preparation and characterization of monoclonal antibodies against ornithine decarboxylase. Journal of Immunological Methods, 1993, 161(2):205-15. |
| Supplier | ARP |
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