| Product Name | Anti-Ovarian Carcinoma-Associated Antigen Monoclonal Antibody |
|---|---|
| Description | Ovarian cancer is a cancerous growth arising from the ovary. Symptoms are frequently very subtle early on and may include: bloating, pelvic pain, difficulty eating and frequent urination, and are easily confused with other illnesses. Antibody OV632 can distinguish ovarian carcinoma from a variety of other tumors. Most primary non-mucinous ovarian adenocarcinomas react with OV632, whereas colon carcinomas and breast carcinomas do not. In surgical pathology the antibody is useful for the discrimination between ovarian and non-ovarian carcinomas both in the ovary and in cases of adenocarcinoma of unknown origin and in the abdomal cavity. |
| Clonality | Monoclonal |
| Clone | OV632 |
| Immunogen | Cyst fluid from a serous cystadenocarcinoma |
| Isotype | IgG2b |
| Specificity | Immunohistochemistry: positive staining in fallopian tube epithelium and follicular cells of ovary. Focal positive staining in epithelial cells from appendix, pancreas and prostate |
| Reactivity | Human |
| Applications | ICC, IHC |
| Form | Stabilized ascites containing 0.1% sodium azide |
| Storage | 2-8C for immediate use, or at -2°C (aliquot) |
| References | Fleuren, GJ et al. (1987) Virchows Arch. A 410: 481-486Koelma, IA et al. (1988) Am. J. Clin. Pathol. 90: 391-396 |
| Background | Ovarian cancer is a cancerous growth arising from the ovary. Symptoms are frequently very subtle early on and may include: bloating, pelvic pain, difficulty eating and frequent urination, and are easily confused with other illnesses. |
| Supplier | ARP |
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