Anti-p40 (deltaNp63) (Squamous, Basal & Myoepithelial Cell Marker), Monoclonal Antibody
| Product Name | Anti-p40 (deltaNp63) (Squamous, Basal & Myoepithelial Cell Marker), Monoclonal Antibody |
|---|---|
| Description | p40 (p63 delta) is a marker recently determined to be highly specific for squamous basal cells in the immunohistochemistry (IHC) application. The current more routinely recommended marker, p63, appears to have less specificity compared to p40, especially on squamous cell tumors. The ability to differentiate between lung adenocarcinoma vs. squamous cell carcinoma is difficult and has bearing on the different therapeutic avenues for each subtype treatment. p63 antibody_Ûªs ability to distinguish between the tumor types appears to be inferior when compared to p40. The ability to utilize an antibody probe for p40 as a squamous cell marker bolsters its use for future sub-classification of lung cancers, especially by immunohistochemical techniques. |
| Synonyms | deltaNp63, TP63 |
| Host | Rabbit |
| Clonality | Monoclonal |
| Immunogen | A synthetic peptide (ENNAQTQFSEPQY) corresponding to aa5-17 of human p40 |
| Isotype | IgG |
| Reactivity | Bovine, Human, Mouse, Rat |
| Applications | FC, IF, IHC, WB |
| Form | 200ug/ml of Ab purified from rabbit anti-serum by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml. |
| Gene Id | 8626 |
| Uniprot | Q9H3D4 |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | Bishop, JA et. al. Modern Pathology 25 : 405Ð4152. Scagliotti G et. al. J Thorac Oncol 6:64Ð70. 3. Kargi A et. al. Appl Immunohistochem Mol Morphol 15:415Ð420 |
| Supplier | ARP |
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